WASHINGTON, D.C. — The Advanced Research Projects Agency for Health has launched a five-year initiative aimed at accelerating biomedical research using artificial intelligence to improve understanding of chronic and complex diseases such as Alzheimer’s disease, Parkinson’s disease and lupus.
The program, called Intelligent Generator of Research, or IGoR, will create an AI-powered research ecosystem designed to speed scientific discovery, improve reproducibility and expand the types of experiments researchers can perform. The agency said the effort is intended to address longstanding inefficiencies in biomedical research, including fragmented data systems and difficulty reproducing study results.
Robert F. Kennedy Jr. said the initiative is intended to improve scientific rigor and transparency.
“IGoR will strengthen transparency, enforce reproducibility, and accelerate discovery—delivering the evidence we need to Make America Healthy Again,” Kennedy said.
According to ARPA-H, the program will support teams working in computational biology, artificial intelligence, machine learning, experimental science and laboratory infrastructure. Researchers will develop mechanistic disease models and AI systems capable of identifying missing information and recommending experiments to address knowledge gaps.
The agency also plans to establish standardized experimental protocols and create a network of laboratories capable of reproducing and validating results across institutions. Data generated through the system would continuously refine disease models over time.
Alicia Jackson said the goal is to modernize how biomedical evidence is generated and shared.
“Americans deserve science that is transparent, efficient, replicable, rigorous, and worthy of the hope patients place in it,” Jackson said. “With IGoR, ARPA-H will modernize how evidence is generated, shared, and validated.”
Paul E. Sheehan said the initiative is intended to expand researchers’ ability to study increasingly complex medical problems.
“Through ARPA-H’s new IGoR program, we can amplify human creativity by reimagining the research ecosystem and empowering our scientists to answer ever more challenging questions about medicine’s unsolved mysteries,” Sheehan said.
The agency said the program will seek proposals through ARPA-H’s Innovative Solutions Opening and encouraged collaboration across scientific disciplines.
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