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Clinical trials

Mineralys Therapeutics
Regional

Mineralys Completes Enrollment in Phase 2 Sleep Apnea and Hypertension Trial

October 5, 2025October 4, 2025 - by Timothy Alexander

RADNOR, PA — Mineralys Therapeutics, Inc. (Nasdaq: MLYS) announced it has completed enrollment in its Phase 2 EXPLORE-OSA trial evaluating lorundrostat in patients with moderate-to-severe obstructive sleep apnea (OSA) and …

Mineralys Completes Enrollment in Phase 2 Sleep Apnea and Hypertension Trial Read More

Larimar Therapeutics
Regional

Larimar Reports Positive Long-Term Data on Nomlabofusp in Friedreich’s Ataxia

October 5, 2025October 4, 2025 - by Timothy Alexander

BALA CYNWYD, PA — Larimar Therapeutics, Inc. (Nasdaq: LRMR) reported new long-term open-label (OL) data for nomlabofusp in Friedreich’s ataxia (FA), showing sustained increases in frataxin (FXN) protein and consistent …

Larimar Reports Positive Long-Term Data on Nomlabofusp in Friedreich’s Ataxia Read More
Medical research
Regional

Aro Biotherapeutics Completes Enrollment in Pompe Disease Trial for ABX1100

October 4, 2025October 2, 2025 - by Timothy Alexander

PHILADELPHIA, PA — Aro Biotherapeutics announced it has completed enrollment in its Phase 1b clinical trial of ABX1100, an investigational therapy for late-onset Pompe disease (LOPD). The study is designed …

Aro Biotherapeutics Completes Enrollment in Pompe Disease Trial for ABX1100 Read More

Harmony Biosciences
Regional

Harmony Biosciences’ Fragile X Trial Falls Short but Offers Key Insights

October 4, 2025October 2, 2025 - by Timothy Alexander

PLYMOUTH MEETING, PA — Harmony Biosciences Holdings, Inc. (Nasdaq: HRMY) reported topline results from its Phase 3 RECONNECT study of ZYN002 in Fragile X syndrome (FXS), announcing that the trial …

Harmony Biosciences’ Fragile X Trial Falls Short but Offers Key Insights Read More
Palvella Therapeutics
Research

Palvella Expands QTORIN Rapamycin Program Into Rare Angiokeratomas

September 29, 2025September 28, 2025 - by Timothy Alexander

WAYNE, PA — Palvella Therapeutics, Inc. (Nasdaq: PVLA) announced it will expand development of its investigational therapy QTORIN™ 3.9% rapamycin anhydrous gel into clinically significant angiokeratomas, a rare and debilitating …

Palvella Expands QTORIN Rapamycin Program Into Rare Angiokeratomas Read More

Palvella Therapeutics
Research

Palvella Completes Phase 2 Trial of QTORIN Rapamycin for Cutaneous Venous Malformations

September 28, 2025September 27, 2025 - by Timothy Alexander

WAYNE, PA — Palvella Therapeutics, Inc. (Nasdaq: PVLA) announced it has completed TOIVA, a Phase 2 proof-of-concept trial of QTORIN™ 3.9% rapamycin anhydrous gel, for the treatment of cutaneous venous …

Palvella Completes Phase 2 Trial of QTORIN Rapamycin for Cutaneous Venous Malformations Read More
Medical news
Regional

Geneos Reports Long-Term Cancer Survivors on Personalized Immunotherapy

September 27, 2025September 27, 2025 - by Timothy Alexander

PHILADELPHIA, PA — Geneos Therapeutics announced that two patients with aggressive cancers have achieved long-term survival on its personalized immunotherapy for cancer (PIC) monotherapy, with one patient living more than …

Geneos Reports Long-Term Cancer Survivors on Personalized Immunotherapy Read More

AstraZeneca
Regional

AstraZeneca Reports Positive Phase III Data for Subcutaneous Lupus Therapy

September 26, 2025September 25, 2025 - by Timothy Alexander

WILMINGTON, DE — AstraZeneca announced positive interim results from its Phase III TULIP-SC trial showing that subcutaneous administration of SAPHNELO (anifrolumab) significantly reduced disease activity in patients with systemic lupus …

AstraZeneca Reports Positive Phase III Data for Subcutaneous Lupus Therapy Read More
Incyte
Regional

Incyte Reports Positive 24-Week Data for Povorcitinib in Hidradenitis Suppurativa

September 26, 2025September 25, 2025 - by Timothy Alexander

WILMINGTON, DE — Incyte (Nasdaq: INCY) released new 24-week interim data from its pivotal Phase 3 STOP-HS trials, showing that its oral JAK1 inhibitor povorcitinib (INCB54707) delivered sustained efficacy and …

Incyte Reports Positive 24-Week Data for Povorcitinib in Hidradenitis Suppurativa Read More
Johnson & Johnson
Regional

Johnson & Johnson’s Oral Psoriasis Drug Shows Superiority in Phase 3 Trials

September 23, 2025September 21, 2025 - by Timothy Alexander

SPRING HOUSE, PA — Johnson & Johnson (NYSE: JNJ) reported new Phase 3 data showing its investigational oral therapy icotrokinra achieved superior skin clearance compared to deucravacitinib in patients with …

Johnson & Johnson’s Oral Psoriasis Drug Shows Superiority in Phase 3 Trials Read More

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