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Clinical trials

Aprea Therapeutics
Regional

Aprea Advances Dual DDR Programs as Early Signals of Drug Activity Strengthen

November 19, 2025November 17, 2025 - by Timothy Alexander

DOYLESTOWN, PA — Aprea Therapeutics, Inc. (Nasdaq: APRE) reported third-quarter 2025 financial results and highlighted steady progress across its two clinical-stage DNA damage response (DDR) programs, citing emerging signs of …

Aprea Advances Dual DDR Programs as Early Signals of Drug Activity Strengthen Read More

Annovis Bio
Finance

Annovis Rallies Around Phase 3 Alzheimer’s Push as New Data Signals Disease-Modifying Promise

November 19, 2025November 17, 2025 - by Timothy Alexander

MALVERN, PA — Annovis Bio, Inc. (NYSE: ANVS) reported third-quarter 2025 financial results and detailed a series of clinical, operational, and intellectual-property developments that the company says position its lead …

Annovis Rallies Around Phase 3 Alzheimer’s Push as New Data Signals Disease-Modifying Promise Read More
Prelude Therapeutics
Regional

Prelude Advances Two Novel Cancer Programs as Cash Runway Extends Into 2027

November 19, 2025November 17, 2025 - by Timothy Alexander

WILMINGTON, DE — Prelude Therapeutics Incorporated (Nasdaq: PRLD) reported third-quarter 2025 financial results and outlined key progress across its oncology pipeline, including two drug candidates now moving toward clinical development …

Prelude Advances Two Novel Cancer Programs as Cash Runway Extends Into 2027 Read More

Palvella Therapeutics
Finance

Palvella Races Toward Key 2026 Readouts as Rare-Disease Pipeline Expands Rapidly

November 18, 2025November 17, 2025 - by Timothy Alexander

WAYNE, PA — Palvella Therapeutics, Inc. (Nasdaq: PVLA) reported third-quarter results and detailed an intensifying slate of clinical milestones as its QTORIN platform advances across four rare dermatologic diseases — …

Palvella Races Toward Key 2026 Readouts as Rare-Disease Pipeline Expands Rapidly Read More
Passage Bio
Regional

Passage Bio Pushes Toward Key 2026 Milestones as Gene Therapy Program Accelerates

November 18, 2025November 17, 2025 - by Timothy Alexander

PHILADELPHIA, PA — Passage Bio, Inc. (Nasdaq: PASG) reported third-quarter financial results and outlined steady progress across its upliFT-D gene therapy program, positioning the company for critical regulatory and clinical …

Passage Bio Pushes Toward Key 2026 Milestones as Gene Therapy Program Accelerates Read More

Mineralys Therapeutics
Regional

Mineralys Nears Pivotal FDA Filing as Hypertension Drug Lorundrostat Advances

November 18, 2025November 17, 2025 - by Timothy Alexander

RADNOR, PA — Mineralys Therapeutics, Inc. (Nasdaq: MLYS) reported third-quarter financial results and said it is preparing to submit a New Drug Application (NDA) for its lead candidate, lorundrostat, by …

Mineralys Nears Pivotal FDA Filing as Hypertension Drug Lorundrostat Advances Read More
Vittoria Biotherapeutics
Regional

New CAR-T Data Could Upend T-Cell Lymphoma Care — Vittoria Prepares First Reveal

November 18, 2025November 17, 2025 - by Timothy Alexander

PHILADELPHIA, PA — Vittoria Biotherapeutics, Inc. announced it will present interim clinical data from its first-in-human Phase 1 study of VIPER-101, a CD5-modulated autologous CAR-T therapy, at the upcoming American …

New CAR-T Data Could Upend T-Cell Lymphoma Care — Vittoria Prepares First Reveal Read More

Verrica Pharmaceuticals Inc
Cancer / Research

New Cancer Data Hints at a Surgery-Free Future — Verrica’s VP-315 Shows Big Promise

November 18, 2025November 17, 2025 - by Timothy Alexander

WEST CHESTER, PA — Verrica Pharmaceuticals Inc. (Nasdaq: VRCA) unveiled compelling new data from its Phase 2 study of VP-315, a first-in-class oncolytic peptide immunotherapy, showing strong local immune activation …

New Cancer Data Hints at a Surgery-Free Future — Verrica’s VP-315 Shows Big Promise Read More
AstraZeneca
Regional

AstraZeneca’s Fasenra Shows Major Breakthrough in Delaying HES Disease Flares

November 18, 2025November 16, 2025 - by Timothy Alexander

WILMINGTON, DE — AstraZeneca reported statistically significant Phase III results showing that Fasenra (benralizumab) can substantially delay disease worsening for patients with hypereosinophilic syndrome (HES), a rare and potentially life-threatening …

AstraZeneca’s Fasenra Shows Major Breakthrough in Delaying HES Disease Flares Read More
Madrigal Pharmaceuticals
Regional

Breakthrough Liver Drug Shows Powerful Two-Year Gains — But Raises a Critical Warning

November 18, 2025November 17, 2025 - by Timothy Alexander

CONSHOHOCKEN, PA — Madrigal Pharmaceuticals, Inc. (NASDAQ: MDGL) unveiled new two-year data showing that its flagship therapy Rezdiffra produced sustained improvements in patients with compensated MASH cirrhosis, a population with …

Breakthrough Liver Drug Shows Powerful Two-Year Gains — But Raises a Critical Warning Read More

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