Aprea Therapeutics Hosts Virtual Event on Promising Cancer Therapy

Aprea Therapeutics

DOYLESTOWN, PAAprea Therapeutics, Inc. (Nasdaq: APRE) will host a virtual Key Opinion Leader (KOL) event on June 24, 2024, at 9:00 AM ET to discuss APR-1051, their highly selective oral WEE1 inhibitor. The event will delve into the drug’s design and preclinical findings, positioning it as a potential best-in-class treatment for oncology.

Joseph Vacca, PhD, a medicinal chemistry expert and consultant to Aprea, will lead the discussion. Dr. Vacca has an illustrious career in drug development, contributing to numerous approved medications during his 30 years at Merck Research Laboratories. His insights into the chemistry behind APR-1051 will shed light on its development and therapeutic potential.

Eric J. Brown, PhD, from the University of Pennsylvania, will also present. Dr. Brown specializes in cancer biology and focuses on the DNA damage response pathway, which WEE1 inhibitors target. His research aims to improve the efficacy of these inhibitors by understanding the genetic changes that affect their performance.

APR-1051 is designed to limit off-target toxicity, making it a promising candidate for treating patients with significant unmet medical needs, including those with Cyclin E overexpression. Aprea recently initiated the Phase 1 ACESOT-1051 trial to evaluate APR-1051 as a monotherapy in such patients.

The event will include a live question-and-answer session following the presentations, allowing participants to engage directly with the experts.

Dr. Vacca’s extensive background includes developing key drugs like CRIXIVAN™ and Isentress™ at Merck. He has received numerous awards and holds over 100 publications and patents. His expertise is expected to provide valuable insights into APR-1051’s development.

Dr. Brown’s work at Penn involves understanding how replication stress responses impact genome stability. His research aims to identify genetic changes that enhance the effectiveness of ATR and WEE1 inhibitors, which could improve patient outcomes.

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Aprea Therapeutics’ APR-1051: Pioneering Cancer Therapy on the Horizon

The DSMB’s recent approval to advance dosing in the current trial phase marks a crucial step forward. With no serious adverse events reported so far, the therapy holds promise for those battling various cancers.

This virtual event emphasizes Aprea’s dedication to advancing cancer treatment through innovative therapies like APR-1051. By bringing together top experts, the company aims to educate the public and medical community about the significant progress being made.

For Aprea, the success of APR-1051 could translate into a breakthrough in cancer therapy. Effective WEE1 inhibitors can potentially change the treatment landscape for various cancers, offering hope to many patients with limited options.

In conclusion, Aprea Therapeutics’ KOL event on June 24 will provide an in-depth look at APR-1051, highlighting its potential as a groundbreaking cancer therapy. With insights from leading experts, the event promises to be a significant step in the fight against cancer. To register, click here.

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