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Regional

Get the Latest News About Southeastern Pennsylvania With MyChesCo’s Regional News

The Most Reliable Source for Local News & Information

Local Coverage You Can Trust

MyChesCo’s Regional News is your go-to source for news and information about southeastern Pennsylvania. Our team of reporters and editors are all based in the region, so we have an intimate understanding of the issues that matter to our readers. Our coverage includes everything from local politics and business to education and the arts, and we strive to ensure that our readers always get the most accurate and up-to-date information.

Comprehensive Coverage of the Region

We cover all the major cities and towns in southeastern Pennsylvania, including Philadelphia, Bucks County, Berks County, Cecil County, Maryland, Delaware County, Montgomery County, Wilmington, Delaware, and New Castle County, Delaware. Our team works hard to track down the facts and deliver comprehensive coverage of the region.

All the Regional News You Need in One Place

MyChesCo’s Regional News is your one-stop shop for reliable news and information about southeastern Pennsylvania. Whether you’re looking for breaking news or in-depth analysis, you’ll find everything you need all in one place. So don’t wait – start exploring our Regional News section today and stay informed about what’s happening in southeastern Pennsylvania.

Travel Restrictions
Regional

SEPTA Rail Work to Shut Down Part of Lancaster Avenue

October 4, 2025October 3, 2025 - by Alec Robson

PHILADELPHIA, PA — SEPTA announced that rail improvement work will close a section of Lancaster Avenue in Philadelphia starting Saturday, October 12.

SEPTA Rail Work to Shut Down Part of Lancaster Avenue Read More

Arrested
Crime / Regional

Three Charged in Connection With Series of Retail Thefts at Morgantown Walmart

October 4, 2025October 4, 2025 - by Zainuddin Harinder

MORGANTOWN, PA — Caernarvon Township Police announced charges against multiple individuals following an investigation into a string of retail thefts that occurred at a Walmart in Berks County throughout August.

Three Charged in Connection With Series of Retail Thefts at Morgantown Walmart Read More
Lane restrictions
Regional

Lane Closures Scheduled on U.S. 1 in Chadds Ford Twp

October 4, 2025October 4, 2025 - by Alec Robson

CHADDS FORD, PA — The Pennsylvania Department of Transportation (PennDOT) announced weekday lane closures on U.S. 1 (Baltimore Pike) in Chadds Ford Township as part of a local safety improvement …

Lane Closures Scheduled on U.S. 1 in Chadds Ford Twp Read More

CSC
Regional

CSC Earns Top Honors in New York Law Journal’s “Best Of” Survey

October 4, 2025October 2, 2025 - by Timothy Alexander

WILMINGTON, DE — CSC has once again secured top recognition in the New York Law Journal’s annual “Best Of” survey, earning high rankings in two key categories.

CSC Earns Top Honors in New York Law Journal’s “Best Of” Survey Read More
Violet crime
Crime / Regional

Wilmington Police Investigating Early Morning Shooting

October 4, 2025October 4, 2025 - by Zainuddin Harinder

WILMINGTON, DE — Wilmington Police are investigating a shooting that occurred early Friday morning in the city.

Wilmington Police Investigating Early Morning Shooting Read More

Mid Penn Bank
Regional

Mid Penn Bank Taps Abe Ibrahim to Lead Central Philadelphia Expansion

October 4, 2025October 3, 2025 - by Timothy Alexander

PHILADELPHIA, PA — Mid Penn Bank, a subsidiary of Mid Penn Bancorp, Inc. (NASDAQ: MPB), has appointed Abe Ibrahim as first senior vice president and regional president of the Central …

Mid Penn Bank Taps Abe Ibrahim to Lead Central Philadelphia Expansion Read More
Medical research
Regional

Aro Biotherapeutics Completes Enrollment in Pompe Disease Trial for ABX1100

October 4, 2025October 2, 2025 - by Timothy Alexander

PHILADELPHIA, PA — Aro Biotherapeutics announced it has completed enrollment in its Phase 1b clinical trial of ABX1100, an investigational therapy for late-onset Pompe disease (LOPD). The study is designed …

Aro Biotherapeutics Completes Enrollment in Pompe Disease Trial for ABX1100 Read More

Harmony Biosciences
Regional

Harmony Biosciences’ Fragile X Trial Falls Short but Offers Key Insights

October 4, 2025October 2, 2025 - by Timothy Alexander

PLYMOUTH MEETING, PA — Harmony Biosciences Holdings, Inc. (Nasdaq: HRMY) reported topline results from its Phase 3 RECONNECT study of ZYN002 in Fragile X syndrome (FXS), announcing that the trial …

Harmony Biosciences’ Fragile X Trial Falls Short but Offers Key Insights Read More
FORE Biotherapeutics
Regional

Fore Bio’s Plixorafenib Clears Interim Review in Brain Tumor Trial

October 4, 2025October 2, 2025 - by Timothy Alexander

PHILADELPHIA, PA — FORE Biotherapeutics announced that its investigational therapy plixorafenib has cleared an interim efficacy analysis in the Phase 2 FORTE basket study for patients with recurrent or progressive …

Fore Bio’s Plixorafenib Clears Interim Review in Brain Tumor Trial Read More
AstraZeneca
Regional

FDA Grants Priority Review for ENHERTU Combo in Advanced Breast Cancer

October 3, 2025October 2, 2025 - by Timothy Alexander

WILMINGTON, DE — AstraZeneca and Daiichi Sankyo announced that the U.S. Food and Drug Administration (FDA) has accepted and granted Priority Review to their supplemental Biologics License Application (sBLA) for …

FDA Grants Priority Review for ENHERTU Combo in Advanced Breast Cancer Read More

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