CONSHOHOCKEN, PA — A newly published case series in the Journal of Wound Care is drawing attention to the growing threat of chronic wounds — and to a promising treatment that may reshape how clinicians manage some of the most stubborn and life-altering wound types.
The report, “Application of a full-thickness placental allograft in complex wound management,” evaluated completeFT™, a dehydrated, full-thickness placental allograft used alongside standard wound care. The analysis underscores the severity of chronic wounds, noting that patients with diabetic foot ulcers face mortality rates five times higher than those diagnosed with breast or prostate cancer. Nearly half of patients who undergo amputations due to DFUs do not survive beyond five years. Venous leg ulcers show similarly difficult trajectories, often healing slowly and deteriorating quickly.
The study tracked 114 patients, average age 73, with 184 complex wounds spanning diabetic foot ulcers, venous leg ulcers, pressure ulcers, surgical wounds, and other classifications. Weekly applications of completeFT™ resulted in consistent reductions in wound size across all categories.
According to the data, 124 wounds showed more than 70% reduction by the final application. Among wounds receiving one to five applications, 31.5% shrank by 60% to 100%. For those receiving six to ten applications, 68.5% saw reductions between 71.4% and 98.3%. Statistical significance was confirmed across wound types, including surgical wounds.
Garrett Grinsfelder, president of Tiger Wound Care, said the results demonstrate that full-thickness placental allografts can play a meaningful role in reducing wound size and mitigating the downstream risks associated with severe wounds. He said the findings point to the potential for fewer amputations, decreased hospitalizations, and lower overall healthcare utilization.
The publication notes that placental allografts are adaptable and easy to apply, making them suitable for a range of clinical environments, including mobile care. The study highlights that improvements were observed regardless of wound type, suggesting broad applicability for completeFT™ in complex wound management.
The full study is available at the Journal of Wound Care website.
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