BLUE BELL, PA — inTRAvent Medical Partners LP announced new peer-reviewed data showing that its SOLOPASS® 2.0 ultrasound-guided neuronavigation platform delivers dramatically higher accuracy than traditional freehand techniques used for external ventricular drain (EVD) placement, a critical neurosurgical procedure often performed under urgent conditions.
The study, published Nov. 13 in Neurosurgery, compared freehand ventricular targeting with SOLOPASS 2.0 using a double-blinded, prospective, paired design. Twenty-five participants — from first-year medical students to experienced neurosurgeons — performed simulated EVD placements on life-sized cranial models.
The differences were stark. Ninety-eight percent of SOLOPASS-guided placements successfully entered the ventricular system, compared with just 10% using freehand methods. Eighty-six percent of SOLOPASS placements reached the intended ipsilateral frontal horn target, while only 8% did so manually. The average miss margin for SOLOPASS was under 0.5 mm, versus nearly 8 mm for freehand placement.
Importantly, SOLOPASS 2.0 delivered consistent first-pass accuracy across all experience levels, demonstrating the system’s potential to standardize outcomes and reduce dependency on operator skill — a major challenge in emergency and critical care settings.
“These findings highlight the transformative potential of ultrasound-guided neuronavigation for safer, more precise ventricular access,” said Dr. Kevin Foley, inTRAvent’s chief innovation officer. He noted that real-time imaging on an intuitive platform can help clinicians place drains more reliably, even in high-stakes, time-sensitive situations.
Dr. Adam Arthur, the company’s chief clinical strategy officer, said the study reinforces inTRAvent’s focus on improving safety and precision in neurosurgery. Integrating portable ultrasound into bedside procedures, he said, can reduce complications and expand access to high-quality care across diverse hospital environments.
SOLOPASS 2.0 is designed to support neurosurgeons, intensivists, and emergency clinicians by delivering a simplified, high-accuracy approach to one of the most technically demanding procedures in acute neurologic care.
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