Mineralys Therapeutics to Present Phase 2 Advance-HTN Trial Data at ACC.25

Mineralys Therapeutics

RADNOR, PA — Mineralys Therapeutics, Inc. (Nasdaq: MLYS) has announced that its Phase 2 Advance-HTN trial data will be presented during a late-breaking clinical trials session at the American College of Cardiology’s Annual Scientific Session & Expo (ACC.25). The high-profile conference will take place in Chicago from March 29 to March 31, 2025.

The trial focuses on evaluating the efficacy and safety of lorundrostat, a novel aldosterone synthase inhibitor, for the treatment of uncontrolled hypertension (uHTN) and resistant hypertension (rHTN). These conditions remain a significant challenge for patients and healthcare providers, emphasizing the importance of innovative therapeutic developments like lorundrostat.

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The study’s presentation will be delivered by Luke Laffin of the Cleveland Clinic Foundation, representing the Advance-HTN investigators. Details for the session include:

  • Abstract Title: Efficacy of Lorundrostat, A Novel Aldosterone Synthase Inhibitor, in Patients With Uncontrolled Hypertension on a Standardized Antihypertensive Medication Regimen
  • Presenter: Luke Laffin, Advance-HTN Investigators, Cleveland Clinic Foundation
  • Session Date/Time: Saturday, March 29, from 1:45 p.m. to 1:55 p.m. CT
  • Session Title: Late-Breaking Clinical Trials III (Session 104)
  • Session Location: Main Tent, North Hall B

The scheduled presentation of this data at ACC.25 underscores its potential impact within the field of cardiovascular medicine. Lorundrostat’s performance in addressing tough-to-treat hypertension could pave the way for new standard-of-care solutions.

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This represents a significant milestone for Mineralys Therapeutics as it works to bring innovative therapies to the hypertension market, addressing a critical and underserved medical need.

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