HARRISBURG, PA — A $450 million investment to build a new pharmaceutical manufacturing facility in Philadelphia is expected to create 225 jobs and expand the production of materials used in cancer treatments, state officials announced.
What This Means for You
- New jobs are coming to the Philadelphia region over the next three years
- The facility will produce materials used in advanced cancer treatments
- State funding and tax incentives helped secure the project
Governor Josh Shapiro said TerraPower Isotopes will build a radioisotope manufacturing facility in the Bellwether District, a large redevelopment site in South and Southwest Philadelphia.
Radioisotopes are radioactive materials used in medicine to diagnose and treat diseases, including targeted cancer therapies that deliver radiation directly to tumors.
What the Facility Will Produce
The plant will manufacture actinium-225, a rare isotope used in emerging cancer treatments known as targeted alpha therapies.
These therapies are designed to deliver precise doses of radiation to cancer cells while minimizing damage to surrounding healthy tissue.
The company plans to lease a 250,000-square-foot facility at the Bellwether District, a 1,300-acre redevelopment of the former Philadelphia Energy Solutions refinery site.
Why Philadelphia Was Selected
State officials said the company evaluated more than 350 locations nationwide before selecting Philadelphia, including dozens of site visits across multiple metropolitan areas.
The Bellwether District is being developed as a hub for advanced manufacturing and innovation, with access to major highways, rail lines, and port infrastructure.
State Support and Incentives
The Commonwealth is investing $10 million in the project through grants, including funding from the PA SITES program and the Pennsylvania First program.
A Keystone Opportunity Zone designation at the site also provides tax incentives through 2043. Keystone Opportunity Zones are areas where businesses can receive reduced or eliminated state and local taxes to encourage development.
The state has also committed $40 million in transportation infrastructure funding to support road improvements around the site.
Economic and Industry Impact
State officials said the project is part of a broader effort to grow Pennsylvania’s life sciences sector, which includes companies focused on biotechnology, pharmaceuticals, and medical research.
“TerraPower Isotopes’ decision to establish a major manufacturing facility in Philadelphia will create hundreds of good-paying jobs while strengthening the Commonwealth’s robust life sciences ecosystem,” said Department of Community and Economic Development Secretary Rick Siger.
Philadelphia Mayor Cherelle Parker said the project will expand economic opportunity and strengthen the city’s manufacturing base.
Next Steps
The facility is expected to be developed over the next several years, with job creation projected within three years as construction and operations ramp up.
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