Zynerba Pharmaceuticals Presents Long-Term Safety and Efficacy Data of Zygel in Children and Adolescents

Zynerba Pharmaceuticals

DEVON, PA — Zynerba Pharmaceuticals, Inc. (Nasdaq: ZYNE) recently presented a poster at the 2022 Society of Biological Psychiatry (SOBP) Annual Meeting, held April 28-30, 2022, in New Orleans, La., and virtually. A copy of the poster is available on the Zynerba corporate website at http://zynerba.com/publications/.

The poster titled, “Long-Term Safety and Sustained Efficacy of ZYN002 Cannabidiol Transdermal Gel in Children and Adolescents with Fragile X Syndrome (ZYN2-CL-017),” shows that in the ongoing long-term safety and efficacy study of Zygel in children and adolescents with FXS, Zygel was well-tolerated with long-term administration with up to 38 months of exposure. The efficacy data were evaluated through 15 months of treatment demonstrating meaningful improvement in social avoidance; with the greatest improvement being seen in patients with complete methylation of their FMR1 gene.

“The data from our long-term open-label study in patients with Fragile X syndrome continue to demonstrate that Zygel has the potential to meaningfully improve the behavioral symptoms of the most impacted individuals in this vulnerable population of children and adolescents,” said Armando Anido, Chairman and Chief Executive Officer of Zynerba. “We are committed to bringing this promising therapy to patients and their families within the Fragile X community.”

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