Virpax Announces Positive Preclinical Toxicology Results in Support of Molecular Envelope Technology

Virpax Pharmaceuticals

BERWYN, PAVirpax® Pharmaceuticals, Inc. (NASDAQ: VRPX) announced that the Company has recently completed FDA-required preclinical toxicology studies for its licensed Molecular Envelope Technology (MET). MET enhances the delivery of Virpax’s non-addictive pain product and its epilepsy product candidate. MET is also utilized in the Company’s viral barrier product candidate. These preclinical toxicology studies were performed to evaluate the safety of the MET platform and to support the IND submission of each product candidate.

The Molecular Envelope Technology was developed by Nanomerics Ltd., a UK-based nanotechnology research and development company. Nanomerics has licensed its technology to Virpax, which is utilizing the nose-to-brain MET platform to enhance drug delivery for certain of its product candidates.

“We are working with a variety of CROs and scientific and pharmaceutical industry leaders to help us evaluate the safety of the MET platform, which underpins a number of our current drug development efforts such as AnQlar which is our viral barrier product candidate. We anticipate that MET will also be a part of our plans for current and future drug development programs. We have engaged Dr. Jeffrey Murray, a leading expert in infectious diseases who spent almost 30 years of his career with the FDA, including as the Deputy Division Director for the Division of Antivirals, Center for Drug Evaluation and Research. Dr. Murray has published many articles related to antivirals and served as a reviewer for the New England Journal of Medicine while at FDA. He has been a valuable contributor to us in the antiviral area in addition to clinical trial design,” commented Dr. Sheila A. Mathias, Chief Scientific Officer for Virpax.

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“We are using the MET platform for EnveltaAnQlar and NobrXiol and expect to use it in other future programs. This patented technology is designed to deliver drug molecules to the brain while reducing degradation during their intranasal transport past the blood-brain barrier. We believe that this drug delivery technology will lessen drug-to-drug interaction and reduce drug dosing. We will be moving these programs to the clinic and appreciate the support of the Virpax team as well as the leading physicians and researchers who are working side by side with us,” concluded Anthony P. Mack, Chairman and CEO of Virpax.

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