Aclaris Therapeutics and Pediatrix Therapeutics Announce License Agreement for ATI-1777 in Greater China

Aclaris Therapeutics

WAYNE, PA — Aclaris Therapeutics, Inc. (NASDAQ: ACRS) and Pediatrix Therapeutics, Inc. this week announced that the companies have entered into a license agreement. Under the license agreement, Aclaris has granted Pediatrix the exclusive rights to develop, manufacture and commercialize ATI-1777, Aclaris’ investigational “soft” Janus kinase (JAK) 1/3 inhibitor, for any disease, including atopic dermatitis, in Greater China (Mainland China, Hong Kong, Macau and Taiwan). Aclaris will retain the rights to develop, manufacture and commercialize ATI-1777 in the rest of the world.

Under the terms of the agreement, Aclaris will receive an upfront payment of $5 million. In addition, Aclaris is eligible to receive milestone payments of up to $91 million if certain development, regulatory and commercial objectives are achieved. Aclaris is also eligible to receive a tiered royalty ranging from a low-to-high single digit percentage of net sales of ATI-1777 by Pediatrix in Greater China.

“We are very excited to partner ATI-1777 with Pediatrix in Greater China, expanding the potential global reach of our internally developed medicine in an area of continued unmet need,” said Jim Loerop, Chief Business Officer of Aclaris. “This serves as continued validation of the ability of our KINect® drug discovery platform to generate valuable assets with potential to have high patient impact.”

Cheng Zhang, Chief Executive Officer of Pediatrix, added, “As a “soft” JAK 1/3 inhibitor, ATI-1777 could provide patients with atopic dermatitis with a new therapeutic option which minimizes the potential for systemic toxicities. Pediatrix is excited to continue the development of ATI-1777 to bring this innovative product to patients and families in China.”

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